United States President Donald Trump has signed an executive order launching the “Genesis Mission,” a national program designed to accelerate scientific discovery through advanced artificial intelligence. Framing the initiative as the most ambitious science effort since the World War II-era Manhattan Project, the administration positioned AI as the next major battleground in global technological leadership.

The order reflects the White House’s push for a fast-moving, low-regulation environment to help U.S. tech giants stay ahead of China in the race to dominate AI. As part of that strategy, federal officials are exploring ways to block U.S. states from creating their own AI regulations, even warning that federal funding could be withdrawn from states that adopt competing rules.

Under the New Directive

The Department of Energy (DOE) will build an integrated national AI platform that unifies America’s top supercomputers, federal research datasets and scientific facilities. The goal is to speed breakthroughs in areas such as nuclear fusion, quantum technologies, semiconductor manufacturing and biotechnology.

“America is in a race for global technology dominance in the development of artificial intelligence,” the order states, calling AI a critical driver of scientific advancement and economic growth.

Read More| Meta in Talks to Tap Google’s TPU Chips, Signalling a Potential Shift in AI Strategy

At the center of the initiative is the American Science and Security Platform, a secure environment where researchers will be able to access high-performance computing systems, AI modeling tools and expansive federal datasets. These resources will support the development of scientific foundation models capable of automating complex research tasks. The DOE has been directed to prepare a list of 20 national scientific priorities within 60 days. Within nine months, the platform must demonstrate its first operational capability by tackling at least one major scientific challenge from that list.

Also Read| DoT Warns Mobile Users: You’re Liable if Your SIM Is Misused for Cybercrime

Expected Domains

Strategic domains expected to feature prominently include semiconductors, advanced manufacturing, critical materials, biotechnology, nuclear energy and quantum computing — all sectors where the United States faces intensifying competition from China.

The executive order also calls for expanded partnerships with industry, academia and national laboratories, backed by rigorous cybersecurity protections to safeguard sensitive research.